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Altru's Laboratory is a College of American Pathologists (CAP) accredited, high complexity laboratory. The laboratory serves northeastern North Dakota and northwestern Minnesota, and operates and advises several regional clinic laboratories. We also provide outreach laboratory services to non-Altru health facilities in the region.


The main laboratory is in operation 24 hours a day, 7 days a week, 365 days a year. There are pathologists       on-site with anatomic and clinical pathology board certifications. Laboratory staff includes medical laboratory scientists, medical laboratory technicians, lab assistants, phlebotomists, histotechnologists, and cytotechnologists.


Altru Pathology and Laboratory Services

1200 South Columbia Road

Grand Forks, ND 58201

701.780.5130 /Fax 701.780.1473






Chromosomal Microarray, Autopsy/Products of Conception/Stillbirth, Tissue (CMAMT) Useful for:

  • Diagnosis of congenital copy number changes in products of conception, including aneuploidy (ie, trisomy or monosomy) and structural abnormalities
  • Diagnosing chromosomal causes for fetal death
  • Determining recurrence risk of future pregnancy losses
  •  Determining the size, precise breakpoints, gene content, and any unappreciated complexity of abnormalities detected previously by other methods such as conventional chromosome and FISH studies
  • Determining if apparently balanced abnormalities identified by previous conventional chromosome studies have cryptic imbalances, since a proportion of such rearrangements that appear balanced at the resolution of a chromosome study are actually unbalanced when analyzed by higher-resolution chromosomal microarray

HIV-1 Genotypic Integrase Inhibitor Drug Resistance, Plasma (HIVI) Useful for:

  • Identification of HIV-1 genotypic mutations in the integrase region of HIV-1 to predict antiretroviral drug resistance in HIV-1-infected patients receiving integrase strand transfer inhibitors (ie, dolutegravir, elvitegravir, raltegravir)
  • Guiding initiation or change of drug combinations for the treatment of HIV-1 infection

Neuro-Oncology Panel, Tumor (NONTP) Useful for:

  • Identifying mutations that may support a diagnosis for patients with tumors of the central nervous system
  • Identifying mutations that may help determine prognosis for patients with tumors of the central nervous system
  • Identifying central nervous system tumors that may respond to targeted therapies by assessing multiple gene targets simultaneously
  • Identifying specific mutations within genes known to be associated with response or resistance to specific cancer therapies

Thiopurine Methyltransferase (TPMT) Activity Profile, Erythrocytes (TPMT3) Useful for:

  • Detection of individuals with low thiopurine methyltranserase (TPMT) activity who are at risk for excessive myelosuppression or severe hematopoietic toxicity when taking thiopurine drugs
  • Detection of individuals with hyperactive TPMT activity who have therapeutic resistance to thiopurine drugs and may develop hepatotoxicity if treated with these drugs